Over the past two decades, the clinical use of cardiac implantable electronic devices has increased significantly. A growing list of indications for regular pacemakers and an increase in the geriatric population mean that more and more patients are undergoing implantation and changing pacemakers. Therefore a large group of people are at risk of infection. Among the possible infectious complications associated with implantation of pacemakers, infective endocarditis is of particular clinical importance. This is infrequent but very serious complication, in some cases it is deathly dangerous. Despite achievements in diagnostic approaches, the choice of treatment for implant-associated infective endocarditis remains a controversial issue. However, there is growing evidences that the entire stimulation system must be removed under the conditions of an open operation in order to achieve the complete elimination of the infection. In this report, we demonstrate our experience in the surgical treatment of an elderly patient who has experienced repeated implantation of a pacemaker due to the development of infectious electrode endocarditis. Interestingly, on the basis of transesophageal echocardiography, which showed the presence of large vegetations on the electrode, it was decided to perform open surgery, during which the infection of the tricuspid valve was discovered. Conditions of the open operation allowed to perform the procedure of valve replacement.