Transposition of the great arteries (TMA) accounts for 5% of all congenital heart defects and is the most common cardiac cause of cyanosis in the neonatal period. TMA is characterized by the development of discordance of the ventricular arterial junction, in other words, the discharge of the main vessels in this defect is as follows: the aorta – from the right ventricle, and the pulmonary trunk from the left ventricle. In the 1960s to the 1980s, one of the main methods for radical correction of TMA was the Mustard or Senning operation. One of the obvious complications encountered in the early and late period in this type of patients was the presence of concomitant, hemodynamically significant arrhythmia. This article describes pathophysiologists, electrophysiological anatomy in patients with cardiac arrhythmias after radical correction of the transposition of the great vessels.